I think this book should be required reading for everyone. Although Dawkins can be slightly condescending in his writing, his arguments are extremely well put together and bring up a lot of issues that you've probably never thought about. Religion is certainly a touchy subject, but it's one that needs to be discussed, and this book has a lot of fascinating things to say about it.
It's actually remarkable just how much is covered in this relatively quick read: evolution, natural selection, upbringing of children, the atheist lifestyle, morality without religion, the God Hypothesis, religious moderates and fundamentalists, religious history, influence of religion on our language and more. No, you don't have to agree with everything (or anything) Dawkins says to appreciate the book. Just reading his opinions, even if you completely disagree with them, will at least get you to think about the issue of religion in ways you probably haven't before.